Specialties

Technologies

Chirotech has more than 20 years of experience in Chemocatalysis as well as Biocatalysis and has a vast library of enzymes. This gives us an edge to provide cost effective solutions for chiral intermediates and commercialise a number of projects. We have an extremely efficient enzyme production system based on pseudomonas expression technology.

We have expertise in asymmetric hydrogenation with a portfolio of proprietary catalysts and experience in producing commercial quantities of pharmaceutical intermediates. The catalysts can selectively reduce a broad range of substrates very selectively and are complementary to biocatalysis.

Another interesting addition to our toolbox is hydroformylation in both achiral and asymmetric variance. This technology has proven to be readily scalable in a cost efficient way giving access to some unique intermediates. Other catalytic technology used by the team includes the asymmetric alkylation technology developed by Prof Trost for which we have an exclusive license. Chirotech offers activated mPEG material for the conjugation of proteins, antibody fragments and peptides to enhance stability and pharmaco-kinetic properties of biologic drugs. We can readily tailor this product to meet our customer’s requirements.

All of these technologies have enabled us to differentiate our offerings to innovator companies and provide technology enabled manufacturing services.