We support pharmaceutical companies across the value chain of development to manufacturing; from intermediates and drug substances (APIs) to drug product (formulations). CPS has capabilities and extensive experience with complex molecules to understand and solve challenges that impede a new drug’s journey to market. The combination of our experienced scientists, state of the art R&D laboratories, cGMP manufacturing sites and technologies (small molecules, peptides, chirals, HPAPIs, steroids, activated mPEGs and dosage forms) makes CPS your preferred CDMO partner. Our customers have access to a vast product portfolio and an extensive global delivery network.
Route scouting for an enantiomerically enriched Isoflavone
Designing a non infringing route, obtaining the highest enantiomeric purity, low yields, purification and isolation.
Mitigating technical challenges and cost impacts by improved process design
Synthesis of a phase II NCE involved an intermediate with high propensity to racemize and isolated in low yields whereby increasing the cost of the product. In addition, pyrophoric reagents, hydrogenation in specialized reactors, purifications by multiple column chromatography were the major challenges.
How the re-designed synthesis of a complex carbohydrate can reduce cycle time
Complex carbohydrate involving a linear sequence of 10 chemical transformations, unstable intermediates and column chromatographic purifications.